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Effect of Substrate Reduction Therapy in Comparison to Enzyme Replacement Therapy on Immune Aspects and Bone Involvement in Gaucher Disease

Gaucher disease (GD) is caused by mutations in the GBA gene, leading to deficient activity of the lysosomal enzyme glucocerebrosidase. Among all the symptoms across various organ systems, bone disease is a major concern as it causes high morbidity and reduces quality of life. Enzyme replacement ther...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Limgala, Renuka P., Goker-Alpan, Ozlem
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226435/
https://ncbi.nlm.nih.gov/pubmed/32244296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10040526
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