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Early Response to the Plant Toxin Stenodactylin in Acute Myeloid Leukemia Cells Involves Inflammatory and Apoptotic Signaling

Stenodactylin, a highly toxic type 2 ribosome-inactivating protein purified from the caudex of Adenia stenodactyla Harms, is a potential anticancer drug candidate. Previous studies demonstrated that stenodactylin induces apoptosis and necroptosis in treated cells, involving the production of reactiv...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Mercatelli, Daniele, Bortolotti, Massimo, Andresen, Vibeke, Sulen, André, Polito, Letizia, Gjertsen, Bjørn Tore, Bolognesi, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226368/
https://ncbi.nlm.nih.gov/pubmed/32457623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00630
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