53BP1 Accumulation in Circulating Tumor Cells Identifies Chemotherapy-Responsive Metastatic Breast Cancer Patients

Evidence suggests that the DNA end-binding protein p53-binding protein 1 (53BP1) is down-regulated in subsets of breast cancer. Circulating tumor cells (CTCs) provide accessible “biopsy material” to track cell traits and functions and their alterations during treatment. Here, we prospectively monito...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Schochter, Fabienne, Werner, Kim, Köstler, Cäcilia, Faul, Anke, Tzschaschel, Marie, Alberter, Barbara, Müller, Volkmar, Neubauer, Hans, Fehm, Tanja, Friedl, Thomas W.P., Polzer, Bernhard, Janni, Wolfgang, Rack, Brigitte, Wiesmüller, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226269/
https://ncbi.nlm.nih.gov/pubmed/32283863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040930
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