Cytotoxic Effect of Trabectedin In Human Adrenocortical Carcinoma Cell Lines and Primary Cells

Mitotane is the only drug approved for the treatment of adrenocortical carcinoma (ACC). The regimen to be added to mitotane is a chemotherapy including etoposide, doxorubicin, and cisplatin. This pharmacological approach, however, has a limited efficacy and significant toxicity. Evidence indicates t...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Abate, Andrea, Rossini, Elisa, Bonini, Sara Anna, Fragni, Martina, Cosentini, Deborah, Tiberio, Guido Albero Massimo, Benetti, Diego, Hantel, Constanze, Laganà, Marta, Grisanti, Salvatore, Terzolo, Massimo, Memo, Maurizio, Berruti, Alfredo, Sigala, Sandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226156/
https://ncbi.nlm.nih.gov/pubmed/32283844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040928
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