Genetic Deficiency of the Histamine H(4)-Receptor Reduces Experimental Colorectal Carcinogenesis in Mice

Colorectal cancer (CRC), a severe complication of inflammatory bowel diseases, is a common type of cancer and accounts for high mortality. CRC can be modeled in mice by application of the tumor promoter, azoxymethane (AOM), in combination with dextran sodium sulfate (DSS), which are able to induce c...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Schirmer, Bastian, Rother, Tamina, Bruesch, Inga, Bleich, Andre, Werlein, Christopher, Jonigk, Danny, Seifert, Roland, Neumann, Detlef
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226035/
https://ncbi.nlm.nih.gov/pubmed/32276475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040912
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