AKT1 Regulates Endoplasmic Reticulum Stress and Mediates the Adaptive Response of Pancreatic β Cells

Isoforms of protein kinase B (also known as AKT) play important roles in mediating insulin and growth factor signals. Previous studies have suggested that the AKT2 isoform is critical for insulin-regulated glucose metabolism, while the role of the AKT1 isoform remains less clear. This study focuses...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Peng, Zhechu, Aggarwal, Richa, Zeng, Ni, He, Lina, Stiles, Eileen X., Debebe, Anketse, Chen, Jingyu, Chen, Chien-Yu, Stiles, Bangyan L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225563/
https://ncbi.nlm.nih.gov/pubmed/32179553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00031-20
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