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A Multiscale Model to Predict Neuronal Cell Deformation with Varying Extracellular Matrix Stiffness and Topography

INTRODUCTION: Neuronal cells are sensitive to mechanical properties of extracellular matrix (ECM) such as stiffness and topography. Cells contract and exert a force on ECM to detect the microenvironment, which activates the signaling pathway to influence the cell functions such as differentiation, m...

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Pubblicato in:Cell Mol Bioeng
Autori principali: Yasodharababu, Mohan, Nair, Arun K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225237/
https://ncbi.nlm.nih.gov/pubmed/32426060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-020-00615-2
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