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B Cell Intrinsic MyD88 Signals Drive IFN-γ Production from T Cells and Control Switching to IgG2c(1)

The question of whether Ab responses to T-dependent Ags require B cell intrinsic signaling via the main TLR adaptor (MyD88) has become embroiled in confusion. In part this may be related to the methods used to analyze B cell intrinsic signaling. We have used a mixed bone marrow chimera model to gene...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Barr, Tom A., Brown, Sheila, Mastroeni, Pietro, Gray, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224988/
https://ncbi.nlm.nih.gov/pubmed/19542370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803706
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