Native Chromatin Proteomics Reveals Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance

Spatially and functionally distinct domains of heterochromatin and euchromatin play important roles in maintenance of chromosome stability and regulation of gene expression, but a comprehensive knowledge of their composition is lacking. Here we develop a strategy for isolation of native Schizosaccha...

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Publicat a:Mol Cell
Autors principals: Iglesias, Nahid, Paulo, Joao A., Tatarakis, Antonis, Wang, Xiaoyi, Edwards, Amanda L., Bhanu, Natarajan V., Garcia, Benjamin A., Haas, Wilhelm, Gygi, Steven P., Moazed, Danesh
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224636/
https://ncbi.nlm.nih.gov/pubmed/31784357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.10.018
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