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Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation

Chitinases are important enzymes that contribute to the generation of carbon and nitrogen from chitin, a long chain polymer of N-acetylglucosamine that is abundant in insects, fungi, invertebrates and fish. Although mammals do not produce chitin, chitinases have been identified in bacteria that are...

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Publicat a:PLoS Pathog
Autors principals: Rehman, Saima, Grigoryeva, Lubov S., Richardson, Katherine H., Corsini, Paula, White, Richard C., Shaw, Rosie, Portlock, Theo J., Dorgan, Benjamin, Zanjani, Zeinab S., Fornili, Arianna, Cianciotto, Nicholas P., Garnett, James A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224574/
https://ncbi.nlm.nih.gov/pubmed/32365117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008342
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