A seven-gene-deleted African swine fever virus is safe and effective as a live attenuated vaccine in pigs

African swine fever (ASF) is a devastating infectious disease in swine that is severely threatening the global pig industry. An efficacious vaccine is urgently required. Here, we used the Chinese ASFV HLJ/18 as a backbone and generated a series of gene-deleted viruses. The virulence, immunogenicity,...

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Detalhes bibliográficos
Publicado no:Sci China Life Sci
Main Authors: Chen, Weiye, Zhao, Dongming, He, Xijun, Liu, Renqiang, Wang, Zilong, Zhang, Xianfeng, Li, Fang, Shan, Dan, Chen, Hefeng, Zhang, Jiwen, Wang, Lulu, Wen, Zhiyuan, Wang, Xijun, Guan, Yuntao, Liu, Jinxiong, Bu, Zhigao
Formato: Artigo
Idioma:Inglês
Publicado em: Science China Press 2020
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Cover Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7223596/
https://ncbi.nlm.nih.gov/pubmed/32124180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11427-020-1657-9
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