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Melanocortin 4 receptor (MC4R) gene variants in children and adolescents having familial early-onset obesity: genetic and clinical characteristics

Melanocortin 4 receptor gene plays an important role in food intake, energy balance, and weight control. The autosomal dominantly inherited MC4R variants cause obesity by causing hyperphagia and decreased sense of satiety. Homozygous variants are rarely reported, and they cause earlier/severe obesit...

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Bibliografiske detaljer
Udgivet i:Eur J Pediatr
Main Authors: Aykut, Ayça, Özen, Samim, Gökşen, Damla, Ata, Aysun, Onay, Hüseyin, Atik, Tahir, Darcan, Şükran, Özkinay, Ferda
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7223532/
https://ncbi.nlm.nih.gov/pubmed/32185475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00431-020-03630-7
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