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Contributions of Aging to Cerebral Small Vessel Disease

Cerebral small vessel disease (SVD) is characterized by changes in the pial and parenchymal microcirculations. SVD produces reductions in cerebral blood flow and impaired blood-brain barrier function, which are leading contributors to age-related reductions in brain health. End-organ effects are div...

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Veröffentlicht in:Annu Rev Physiol
Hauptverfasser: De Silva, T. Michael, Faraci, Frank M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7223478/
https://ncbi.nlm.nih.gov/pubmed/31618600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-021119-034338
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