Inferring causal gene regulatory networks from coupled single cell expression dynamics using Scribe

Here, we present Scribe (https://github.com/aristoteleo/Scribe-py), a toolkit for detecting and visualizing causal regulatory interactions between genes and explore the potential for single-cell experiments to power network reconstruction. Scribe employs Restricted Directed Information to determine...

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Publicado en:Cell Syst
Main Authors: Qiu, Xiaojie, Rahimzamani, Arman, Wang, Li, Ren, Bingcheng, Mao, Qi, Durham, Timothy, McFaline-Figueroa, José L, Saunders, Lauren, Trapnell, Cole, Kannan, Sreeram
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7223477/
https://ncbi.nlm.nih.gov/pubmed/32135093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.02.003
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