Programmed ‘disarming’ of the neutrophil proteome reduces the magnitude of inflammation

The antimicrobial functions of neutrophils are facilitated by a defensive armamentarium of proteins stored in granules, and by the formation of neutrophil extracellular traps (NETs). However, the toxic nature of these structures poses a threat to highly vascularized tissues, such as the lungs. Here,...

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Publicado no:Nat Immunol
Main Authors: Adrover, Jose M., Aroca-Crevillén, Alejandra, Crainiciuc, Georgiana, Ostos, Fernando, Rojas-Vega, Yeny, Rubio-Ponce, Andrea, Cilloniz, Catia, Bonzón-Kulichenko, Elena, Calvo, Enrique, Rico, Daniel, Moro, María A., Weber, Christian, Lizasoaín, Ignacio, Torres, Antoni, Ruiz-Cabello, Jesús, Vázquez, Jesús, Hidalgo, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7223223/
https://ncbi.nlm.nih.gov/pubmed/31932813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0571-2
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