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Combined endocrine approaches vs endocrine therapy alone as first line treatment in elderly patients with hormone receptor-positive, HER2 negative, advanced breast cancer: to prescribe for the patient or the physician? A meta-analysis of phase II and III randomized clinical trials

BACKGROUND: Elderly patients are underrepresented in clinical study where combined endocrine strategies were compared to endocrine therapy (ET) in hormone receptors positive, HER2 negative, metastatic breast cancer. The role of the new endocrine approaches in elderly women is still unclear. METHODS:...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Cancer
Hauptverfasser: Omarini, Claudia, Piacentini, Federico, Sperduti, Isabella, Barbolini, Monica, Isca, Chrystel, Toss, Angela, Cortesi, Laura, Barbieri, Elena, Dominici, Massimo, Moscetti, Luca
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222291/
https://ncbi.nlm.nih.gov/pubmed/32404154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06933-y
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