Coordination Chemistry of [Y(pypa)](−) and Comparison Immuno-PET Imaging of [(44)Sc]Sc- and [(86)Y]Y-pypa-phenyl-TRC105

Both scandium-44 and yttrium-86 are popular PET isotopes with appropriate half-lives for immuno-positron emission tomography (immuno-PET) imaging. Herein, a new bifunctional H(4)pypa ligand, H(4)pypa-phenyl-NCS, is synthesized, conjugated to a monoclonal antibody, TRC105, and labeled with both radio...

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Publicat a:Dalton Trans
Autors principals: Li, Lily, de Guadalupe Jaraquemada-Peláez, María, Aluicio-Sarduy, Eduardo, Wang, Xiaozhu, Barnhart, Todd E., Cai, Weibo, Radchenko, Valery, Schaffer, Paul, Engle, Jonathan W., Orvig, Chris
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222037/
https://ncbi.nlm.nih.gov/pubmed/32270167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0dt00437e
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