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Cellular adaptation to hypoxia through HIFs and beyond

Molecular oxygen (O(2)) sustains intracellular bioenergetics and is consumed by numerous biochemical reactions, making it essential for most species on Earth. Accordingly, decreased O(2) concentrations (hypoxia) is a major stressor that generally subverts life of aerobic species and is a prominent f...

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Detalhes bibliográficos
Publicado no:Nat Rev Mol Cell Biol
Main Authors: Lee, Pearl, Chandel, Navdeep S., Celeste Simon, M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222024/
https://ncbi.nlm.nih.gov/pubmed/32144406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41580-020-0227-y
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