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In Search of Outliers. Mining for Protein Kinase Inhibitors Based on Their Anti-Proliferative NCI-60 Cell Lines Profile

Protein kinases play a pivotal role in signal transduction, protein synthesis, cell growth and proliferation. Their deregulation represents the basis of pathogenesis for numerous diseases such as cancer and pathologies with cardiovascular, nervous and inflammatory components. Protein kinases are an...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Ion, George Nicolae Daniel, Nitulescu, George Mihai
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221881/
https://ncbi.nlm.nih.gov/pubmed/32290461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25081766
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