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Development and In Vitro and In Vivo Evaluation of Microspheres Containing Sodium N-[8-(2-hydroxybenzoyl)amino]caprylate for the Oral Delivery of Berberine Hydrochloride

Microspheres containing absorption enhancer (sodium N-[8-(2-hydroxybenzoyl)amino]caprylate, SNAC) were developed to enhance the oral bioavailability of berberine hydrochloride (BER) with poor intestinal membrane permeability. Microspheres were prepared and characterized by particle size measurements...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Li, Ying, Zhu, Chunyan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221516/
https://ncbi.nlm.nih.gov/pubmed/32340157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25081957
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