TIMP-2 suppresses tumor growth and metastasis in murine model of triple-negative breast cancer

Metastasis is the primary cause of treatment failures and mortality in most cancers. Triple-negative breast cancer (TNBC) is refractory to treatment and rapidly progresses to disseminated disease. We utilized an orthotopic mouse model that molecularly and phenotypically resembles human TNBC to study...

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Dettagli Bibliografici
Pubblicato in:Carcinogenesis
Autori principali: Peeney, David, Jensen, Sandra M, Castro, Nadia P, Kumar, Sarvesh, Noonan, Silvia, Handler, Chenchen, Kuznetsov, Alex, Shih, Joanna, Tran, Andy D, Salomon, David S, Stetler-Stevenson, William G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Inflammation, Microenvironment and Prevention
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221506/
https://ncbi.nlm.nih.gov/pubmed/31621840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgz172
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