Insulin-like growth factor-1, insulin-like growth factor-binding protein-3, and breast cancer risk: observational and Mendelian randomization analyses with ∼430 000 women

BACKGROUND: Epidemiological evidence supports a positive association between circulating insulin-like growth factor-1 (IGF-1) concentrations and breast cancer risk, but both the magnitude and causality of this relationship are uncertain. We conducted observational analyses with adjustment for regres...

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Veröffentlicht in:Ann Oncol
Hauptverfasser: Murphy, N., Knuppel, A., Papadimitriou, N., Martin, R.M., Tsilidis, K.K., Smith-Byrne, K., Fensom, G., Perez-Cornago, A., Travis, R.C., Key, T.J., Gunter, M.J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221341/
https://ncbi.nlm.nih.gov/pubmed/32169310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.annonc.2020.01.066
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