An FGFR/AKT/SOX2 Signaling Axis Controls Pancreatic Cancer Stemness

Cancer stemness is associated with high malignancy and low differentiation, as well as therapeutic resistance of tumors including pancreatic ductal adenocarcinoma (PDAC). Fibroblast growth factors (FGFs) exert pleiotropic effects on a variety of cellular processes and functions including embryonic s...

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Udgivet i:Front Cell Dev Biol
Main Authors: Quan, Mei-Yu, Guo, Qiang, Liu, Jiayu, Yang, Ruo, Bai, Jing, Wang, Wei, Cai, Yaxin, Han, Rui, Lv, Yu-Qing, Ding, Li, Billadeau, Daniel D., Lou, Zhenkun, Bellusci, Saverio, Li, Xiaokun, Zhang, Jin-San
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221133/
https://ncbi.nlm.nih.gov/pubmed/32457900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00287
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