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BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning
Brown and beige fat share a remarkably similar transcriptional program that supports fuel oxidation and thermogenesis. The chromatin-remodeling machinery that governs genome accessibility and renders adipocytes poised for thermogenic activation remains elusive. Here we show that BAF60a, a subunit of...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7221096/ https://ncbi.nlm.nih.gov/pubmed/32404872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16148-1 |
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