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Targeting the Multiple Physiologic Roles of VDAC With Steroids and Hydrophobic Drugs

There is accumulating evidence that endogenous steroids and non-polar drugs are involved in the regulation of mitochondrial physiology. Many of these hydrophobic compounds interact with the Voltage Dependent Anion Channel (VDAC). This major metabolite channel in the mitochondrial outer membrane (MOM...

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Publicat a:Front Physiol
Autors principals: Rostovtseva, Tatiana K., Queralt-Martín, María, Rosencrans, William M., Bezrukov, Sergey M.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221028/
https://ncbi.nlm.nih.gov/pubmed/32457654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00446
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