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Effects of acute sleep loss on diurnal plasma dynamics of CNS health biomarkers in young men

OBJECTIVE: Disrupted sleep increases CSF levels of tau and β-amyloid (Aβ) and is associated with an increased risk of Alzheimer disease (AD). Our aim was to determine whether acute sleep loss alters diurnal profiles of plasma-based AD-associated biomarkers. METHODS: In a 2-condition crossover study,...

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Détails bibliographiques
Publié dans:Neurology
Auteurs principaux: Benedict, Christian, Blennow, Kaj, Zetterberg, Henrik, Cedernaes, Jonathan
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220231/
https://ncbi.nlm.nih.gov/pubmed/31915189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000008866
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