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The Biology of the HIV-1 Latent Reservoir and Implications for Cure Strategies

Antiretroviral therapy (ART) inhibits HIV replication but is not curative. During ART, the integrated HIV genome persists indefinitely within CD4(+) T cells and perhaps other cells. Here, we describe the mechanisms thought to contribute to its persistence during treatment and highlight findings from...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Cohn, Lillian B., Chomont, Nicolas, Deeks, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219958/
https://ncbi.nlm.nih.gov/pubmed/32272077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.03.014
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