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Low-dose alemtuzumab induction in a tailored immunosuppression protocol for sensitized kidney transplant recipients

BACKGROUND: Induction therapy is crucial in kidney transplantation and constitutes an important cornerstone for long-term allograft survival. Alemtuzumab is a depleting CD52-specific antibody with T- and B-cell activity, leading to prolonged lymphocyte depletion for up to 12 months, with profound im...

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Detalhes bibliográficos
Publicado no:BMC Nephrol
Main Authors: Guthoff, Martina, Berger, Kilian, Althaus, Karina, Mühlbacher, Thomas, Bakchoul, Tamam, Steurer, Wolfgang, Nadalin, Silvio, Königsrainer, Alfred, Heyne, Nils
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218828/
https://ncbi.nlm.nih.gov/pubmed/32404066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-020-01767-z
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