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Improving immunogenicity and safety of flagellin as vaccine carrier by high-density display on virus-like particle surface
Flagellin is a protein-based adjuvant that activates toll-like receptor (TLR) 5. Flagellin has been actively explored as vaccine adjuvants and carriers. Preclinical and clinical studies find flagellin-based vaccines have a risk to induce systemic adverse reactions potentially due to its overt activa...
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| Publicado no: | Biomaterials |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7218678/ https://ncbi.nlm.nih.gov/pubmed/32315864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.120030 |
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