An investigation of genetic polymorphisms in heparan sulfate proteoglycan core proteins and key modification enzymes in an Australian Caucasian multiple sclerosis population

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease affecting the central nervous system in young adults. Heparan sulfate proteoglycans (HSPGs) are ubiquitous to the cell surface and the extracellular matrix. HSPG biosynthesis is a complex process involving enzymatic attachment o...

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Udgivet i:Hum Genomics
Main Authors: Okolicsanyi, Rachel K., Bluhm, Julia, Miller, Cassandra, Griffiths, Lyn R., Haupt, Larisa M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Primary Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218574/
https://ncbi.nlm.nih.gov/pubmed/32398079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-020-00264-6
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