Heterogeneous Drug Efficacy of an Antibody-Drug Conjugate Visualized Using Simultaneous Imaging of Its Delivery and Intracellular Damage in Living Tumor Tissues

Anticancer drug efficacy varies because the delivery of drugs within tumors and tumor responses are heterogeneous; however, these features are often more homogenous in vitro. This difference makes it difficult to accurately determine drug efficacy. Therefore, it is important to use living tumor tiss...

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Bibliografiske detaljer
Udgivet i:Transl Oncol
Main Authors: Gonda, Kohsuke, Negishi, Hiroshi, Takano-Kasuya, Mayumi, Kitamura, Narufumi, Furusawa, Naoko, Nakano, Yasushi, Hamada, Yoh, Tokunaga, Masayuki, Higuchi, Hideo, Tada, Hiroshi, Ishida, Takanori
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press 2020
Fag:
Original article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218300/
https://ncbi.nlm.nih.gov/pubmed/32403030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100764
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