Hyperglycemia contributes to the development of Leydig cell hyperplasia in male Spontaneously Diabetic Torii rats

Spontaneously Diabetic Torii (SDT) rats are a well-known animal model of non-obese type 2 diabetes mellitus. Although this animal model has been studied extensively over the last decade, the incidence rates of Leydig cell hyperplasia and tumors in this model have not been reported. In this study, pa...

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Veröffentlicht in:J Toxicol Pathol
Hauptverfasser: Nakane, Yoshitomi, Kemmochi, Yusuke, Ogawa, Naoto, Sasase, Tomohiko, Ohta, Takeshi, Higami, Yoshikazu, Fukai, Fumio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Japanese Society of Toxicologic Pathology 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218238/
https://ncbi.nlm.nih.gov/pubmed/32425345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2019-0088
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