Definition of miRNA Signatures of Nodal Metastasis in LCa: miR-449a Targets Notch Genes and Suppresses Cell Migration and Invasion

Laryngeal cancer (LCa), a neoplasm of the head and neck region, is a leading cause of death worldwide. Surgical intervention remains the mainstay of LCa treatment, but a crucial point is represented by the possible nodal involvement. Therefore, it is urgently needed to develop biomarkers and therape...

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Bibliographic Details
Published in:Mol Ther Nucleic Acids
Main Authors: Kawasaki, Hiromichi, Takeuchi, Takashi, Ricciardiello, Filippo, Lombardi, Angela, Biganzoli, Elia, Fornili, Marco, De Bortoli, Davide, Mesolella, Massimo, Cossu, Alessia Maria, Scrima, Marianna, Capasso, Rosanna, Falco, Michela, Motta, Giovanni, Motta, Gaetano, Testa, Domenico, De Luca, Stefania, Oliva, Flavia, Abate, Teresa, Mazzone, Salvatore, Misso, Gabriella, Caraglia, Michele
Format: Artigo
Language:Inglês
Published: American Society of Gene & Cell Therapy 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218231/
https://ncbi.nlm.nih.gov/pubmed/32402942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.04.006
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