Transcriptional Suppression of miR-7 by MTA2 Induces Sp1-Mediated KLK10 Expression and Metastasis of Cervical Cancer

MTA2 is involved in tumor proliferation and metastasis. However, the role of MTA2 in cervical cancer thus far has not been identified. In this study, we report that elevated expression of MTA2 negatively correlates with Kallikrein-10 (KLK10) expression and poor prognosis of cervical cancer patients....

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Udgivet i:Mol Ther Nucleic Acids
Main Authors: Lin, Chia-Liang, Ying, Tsung-Ho, Yang, Shun-Fa, Wang, Shih-Wei, Cheng, Shih-Ping, Lee, Jie-Jen, Hsieh, Yi-Hsien
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218230/
https://ncbi.nlm.nih.gov/pubmed/32402941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.04.009
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