HIVconsv Vaccines and Romidepsin in Early-Treated HIV-1-Infected Individuals: Safety, Immunogenicity and Effect on the Viral Reservoir (Study BCN02)

Kick&kill strategies combining drugs aiming to reactivate the viral reservoir with therapeutic vaccines to induce effective cytotoxic immune responses hold potential to achieve a functional cure for HIV-1 infection. Here, we report on an open-label, single-arm, phase I clinical trial, enrolling...

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Publicado en:Front Immunol
Autores principales: Mothe, Beatriz, Rosás-Umbert, Miriam, Coll, Pep, Manzardo, Christian, Puertas, Maria C., Morón-López, Sara, Llano, Anuska, Miranda, Cristina, Cedeño, Samandhy, López, Miriam, Alarcón-Soto, Yovaninna, Melis, Guadalupe Gómez, Langohr, Klaus, Barriocanal, Ana M., Toro, Jessica, Ruiz, Irene, Rovira, Cristina, Carrillo, Antonio, Meulbroek, Michael, Crook, Alison, Wee, Edmund G., Miró, Jose M., Clotet, Bonaventura, Valle, Marta, Martinez-Picado, Javier, Hanke, Tomáš, Brander, Christian, Moltó, José
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218169/
https://ncbi.nlm.nih.gov/pubmed/32435247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00823
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