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Transcriptome Profiling Reveals Indoxyl Sulfate Should Be Culpable of Impaired T Cell Function in Chronic Kidney Disease

Introduction: Chronic inflammation and immune system dysfunction have been evaluated as major factors in the pathogenesis of chronic kidney disease (CKD), contributing to the high mortality rates observed in these populations. Uremic toxins seem to be the potential “missing link.” Indoxyl sulfate (I...

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Bibliografiske detaljer
Udgivet i:Front Med (Lausanne)
Main Authors: Xiang, Fangfang, Cao, Xuesen, Shen, Bo, Chen, Xiaohong, Guo, Man, Ding, Xiaoqiang, Zou, Jianzhou
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218060/
https://ncbi.nlm.nih.gov/pubmed/32435647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2020.00178
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