Human multi-organ chip co-culture of bronchial lung culture and liver spheroids for substance exposure studies

Extrapolation of cell culture-based test results to in vivo effects is limited, as cell cultures fail to emulate organ complexity and multi-tissue crosstalk. Biology-inspired microphysiological systems provide preclinical insights into absorption, distribution, metabolism, excretion, and toxicity of...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Schimek, Katharina, Frentzel, Stefan, Luettich, Karsta, Bovard, David, Rütschle, Isabel, Boden, Laura, Rambo, Felix, Erfurth, Hendrik, Dehne, Eva-Maria, Winter, Annika, Marx, Uwe, Hoeng, Julia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217973/
https://ncbi.nlm.nih.gov/pubmed/32398725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64219-6
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