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Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties

Naked mole-rat (NMR), the longest-living rodent, produces very-high-molecular-mass hyaluronan (vHMM-HA), compared to other mammalian species. However, it is unclear if exceptional polymer length of vHMM-HA is important for longevity. Here, we show that vHMM-HA (>6.1 MDa) has superior cytoprotecti...

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書目詳細資料
發表在:Nat Commun
Main Authors: Takasugi, Masaki, Firsanov, Denis, Tombline, Gregory, Ning, Hanbing, Ablaeva, Julia, Seluanov, Andrei, Gorbunova, Vera
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217962/
https://ncbi.nlm.nih.gov/pubmed/32398747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16050-w
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