Causal association of circulating cholesterol levels with dementia: a mendelian randomization meta-analysis

Prospective studies have shown that abnormally circulating cholesterol is associated with the risk of dementia. However, whether the association is causal or not remains unclear. We attempt to infer the causal association in a MR meta-analysis by using ApoE gene polymorphisms as instrument variables...

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Veröffentlicht in:Transl Psychiatry
Hauptverfasser: Zhang, Xiaoyu, Tian, Qiuyue, Liu, Di, Geng, Tao, Xu, Xizhu, Ge, Siqi, Zheng, Deqiang, Wu, Lijuan, Song, Manshu, Hou, Haifeng, Wang, Wei, Wang, Youxin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217910/
https://ncbi.nlm.nih.gov/pubmed/32398686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-0822-x
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