Prognostic and clinical impact of PD-L2 and PD-L1 expression in a cohort of 437 oesophageal cancers

BACKGROUND: The PD-1/PD-L1 pathway plays critical roles in tumour immunology, and serves as an immune-based therapeutic target. Less is known regarding PD-L2, another ligand of PD-1, and its relation to clinical outcome in human cancers. METHODS: We used a database of 437 surgically and 100 endoscop...

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Veröffentlicht in:Br J Cancer
Hauptverfasser: Okadome, Kazuo, Baba, Yoshifumi, Nomoto, Daichi, Yagi, Taisuke, Kalikawe, Rebecca, Harada, Kazuto, Hiyoshi, Yukiharu, Nagai, Yohei, Ishimoto, Takatsugu, Iwatsuki, Masaaki, Iwagami, Shiro, Miyamoto, Yuji, Yoshida, Naoya, Watanabe, Masayuki, Komohara, Yoshihiro, Shono, Takashi, Sasaki, Yutaka, Baba, Hideo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217865/
https://ncbi.nlm.nih.gov/pubmed/32210369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0811-0
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