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SOX9 interacts with FOXC1 to activate MYC and regulate CDK7 inhibitor sensitivity in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is particularly sensitive to cyclin-dependent kinase 7 inhibitor, THZ1, compared to hormone receptor (HR)+ breast cancer, but our data found that different TNBC cell lines had a wide range of IC(50) values of THZ1, suggesting a possible heterogeneity in sensitivi...
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| Publicado no: | Oncogenesis |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7217837/ https://ncbi.nlm.nih.gov/pubmed/32398735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-0232-1 |
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