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The possible mechanisms of action of 4-aminoquinolines (chloroquine/hydroxychloroquine) against Sars-Cov-2 infection (COVID-19): A role for iron homeostasis?

The anti-malarial drugs chloroquine (CQ) and primarily the less toxic hydroxychloroquine (HCQ) are currently used to treat autoimmune diseases for their immunomodulatory and anti-thrombotic properties. They have also been proposed for the treatment of several viral infections, due to their anti-vira...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Quiros Roldan, Eugenia, Biasiotto, Giorgio, Magro, Paola, Zanella, Isabella
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217799/
https://ncbi.nlm.nih.gov/pubmed/32430286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2020.104904
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