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NK cells prevent T cell lymphoma development in T cell receptor-transgenic mice

Mice that express a single transgenic T cell receptor have a low incidence of T cell lymphoma development. We investigated whether this tumor development is restricted by surveillance mechanisms that are exerted by IL-15-dependent cells. Lymphoma incidence was increased to between 30 and 60% when TC...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Immunol
Prif Awduron: Dubois, Sigrid, Feigenbaum, Lionel, Waldmann, Thomas A., Müller, Jürgen R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217732/
https://ncbi.nlm.nih.gov/pubmed/32143838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2020.104081
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