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Cytochrome P450 2E1 and Its Roles in Disease

Cytochrome P450 (P450) 2E1 is the major P450 enzyme involved in ethanol metabolism. That role is shared with two other enzymes that oxidize ethanol, alcohol dehydrogenase and catalase. P450 2E1 is also involved in the bioactivation of a number of low molecular weight cancer suspects, as validated in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Chem Biol Interact
1. Verfasser: Guengerich, F. Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217708/
https://ncbi.nlm.nih.gov/pubmed/32198084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2020.109056
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