Dimethyl fumarate suppresses granulocyte macrophage colony-stimulating factor–producing Th1 cells in CNS neuroinflammation

OBJECTIVE: To study the immunomodulatory effect of dimethyl fumarate (DF) on granulocyte macrophage colony-stimulating factor (GM-CSF) production in CD4(+) T cells in experimental autoimmune encephalomyelitis (EAE) and human peripheral blood mononuclear cells (PBMCs). METHODS: We collected splenocyt...

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Publicat a:Neurol Neuroimmunol Neuroinflamm
Autors principals: Safavi, Farinaz, Thome, Rodolfo, Li, Zichen, Zhang, Guang-Xian, Rostami, Abdolmohamad
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217662/
https://ncbi.nlm.nih.gov/pubmed/32371548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000729
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