Atorvastatin Reduces In Vivo Fibrin Deposition and Macrophage Accumulation, and Improves Primary Patency Duration and Maturation of Murine Arteriovenous Fistula

BACKGROUND: Arteriovenous fistulas placed surgically for dialysis vascular access have a high primary failure rate resulting from excessive inward remodeling, medial fibrosis, and thrombosis. No clinically established pharmacologic or perisurgical therapies currently address this unmet need. Statins...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Cui, Jie, Kessinger, Chase W., Jhajj, Harkamal S., Grau, Madeleine S., Misra, Sanjay, Libby, Peter, McCarthy, Jason R., Jaffer, Farouc A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2020
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217409/
https://ncbi.nlm.nih.gov/pubmed/32152232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019060612
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