Analysis of Infected Host Gene Expression Reveals Repurposed Drug Candidates and Time-Dependent Host Response Dynamics for COVID-19

The repurposing of existing drugs offers the potential to expedite therapeutic discovery against the current COVID-19 pandemic caused by the SARS-CoV-2 virus. We have developed an integrative approach to predict repurposed drug candidates that can reverse SARS-CoV-2-induced gene expression in host c...

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Veröffentlicht in:bioRxiv
Hauptverfasser: Xing, Jing, Shankar, Rama, Drelich, Aleksandra, Paithankar, Shreya, Chekalin, Evgenii, Dexheimer, Thomas, Chua, Mei-Sze, Rajasekaran, Surender, Tseng, Chien-Te Kent, Chen, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217282/
https://ncbi.nlm.nih.gov/pubmed/32511305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.04.07.030734
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