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Effects of combined treatment with fesoterodine and mirabegron in a pelvic congestion rat model: Results from in vitro and in vivo functional studies

OBJECTIVES: To examine the effect of combining a nonselective muscarinic receptor antagonist, 5‐hydroxymethyl tolterodine (an active metabolite of fesoterodine), with a β3 adrenoceptor agonist, mirabegron, in a rat model of pelvic congestion. METHODS: The rat pelvic congestion model used female Spra...

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Publicat a:Low Urin Tract Symptoms
Autors principals: Sugaya, Kimio, Yamagami, Hidetomi, Nishijima, Saori, Kadekawa, Katsumi, Hizue, Masanori, Ito, Yoshihiko, Yamada, Shizuo
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Asia Pty Ltd 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217205/
https://ncbi.nlm.nih.gov/pubmed/31758673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/luts.12296
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