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Understanding the challenge of comparative effectiveness research in focal epilepsy: A review of network meta‐analyses and real‐world evidence on antiepileptic drugs

OBJECTIVE: Head‐to‐head randomized controlled trials (RCTs) are the gold standard for assessing comparative treatment effects. In the absence of direct comparisons between all possible antiepileptic drugs (AEDs), however, clinical decision‐making in focal (partial onset) epilepsy relies on alternati...

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Опубликовано в: :Epilepsia
Главные авторы: Thieffry, Solène, Klein, Pavel, Baulac, Michel, Plumb, Jonathan, Pelgrims, Barbara, Steeves, Sara, Borghs, Simon
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216985/
https://ncbi.nlm.nih.gov/pubmed/32201951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.16476
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