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Novel IRF6 mutations in Chinese Han families with Van der Woude syndrome

BACKGROUND: Interferon Regulatory Factor 6 (IRF6) gene encodes a member of the IRF family of transcription factors. Mutations in IRF6 cause Van der Woude Syndrome (VWS), which is the most common malformation of syndromic orofacial clefts in humans. METHODS: Here, we performed sequencing studies of s...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: Yu, Yanqin, Wan, Yatao, Qin, Chuanqi, Yue, Haitang, Bian, Zhuan, He, Miao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216816/
https://ncbi.nlm.nih.gov/pubmed/32108996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1196
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